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Anti-Human CD272 (BTLA) Biotin



Catalog Number : 24811-30

Description

The MIH26 monoclonal antibody specifically reacts with human CD272, the human and B and T lymphocyte attenuator (BTLA). It is expressed on macrophage, dendritic, NK, NKT, B, and T cells. CD272 (BTLA) is an inhibitory receptor that inhibits T cell proliferation after binding with its ligand, the herpes virus entry mediator (HVEM). It is in the CD28-like family of receptors and is structurally similar to CTLA-4 and PD-1.

Additional Information

Clone:
MIH26
Format:
Biotin
Applications:
FC
Reactivity:
Human
Isotype:
Mouse IgG2a
Research Interest: Adaptive Immunity
Cell Type: B Cells, Monocytes and Macrophages, T Cells, Dendritic Cells
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Otsuki, N., Kamimura, Y., Hashiguchi, M., & Azuma, M. (2006). Expression and function of the B and T lymphocyte attenuator (BTLA/CD272) on human T cells. Biochemical and biophysical research communications344(4), 1121-1127.

Watanabe, N., Gavrieli, M., Sedy, J. R., Yang, J., Fallarino, F., Loftin, S. K., ... & Murphy, K. M. (2003). BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1. Nature immunology4(7), 670-679.

Sedy, J. R., Gavrieli, M., Potter, K. G., Hurchla, M. A., Lindsley, R. C., Hildner, K., ... & Murphy, K. M. (2005). B and T lymphocyte attenuator regulates T cell activation through interaction with herpesvirus entry mediator. Nature immunology6(1), 90-98.


Availability: In stock

Size Price Qty
25 ug
$120.00
Additional MIH26 Formats
Cat.No. Format Starting From
24811-30Biotin $ 120.00