Anti-Mouse/Rat CD61 (Integrin beta 3) PE

Grouped product items
SizePrice Qty
50ug
$120.00
200ug
$320.00

Additional 2C9.G3 Formats

Cat.No.FormatStarting From
03712-25SAFIRE Purified$ 100.00
03712-60PE$ 120.00
Catalog Number : 03712-60

description

The 2C9.G3 monoclonal antibody specifically reacts with the mouse/rat CD61 molecule, known as the integrin beta 3 that forms the vitronectin receptor with CD51. The complex binds to other ligands such as fibrinogen, fibronectin, thrombospondin, and von WIllebrand factor. It is expressed by granulocytes, platelets, activated T cells, smooth muscle, and a subset of B cells.

Additional Information

Clone:
2C9.G3
Format:
PE
Applications:
FC
Reactivity:
Mouse, Rat
Isotype:
Armenian Hamster IgG
Research Interest:Adaptive Immunity, Angiogenesis
Application:FC
Clone:2C9.G3
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Vaillant, F., Asselin-Labat, M. L., Shackleton, M., Forrest, N. C., Lindeman, G. J., & Visvader, J. E. (2008). The mammary progenitor marker CD61/β3 integrin identifies cancer stem cells in mouse models of mammary tumorigenesis.Cancer research68(19), 7711-7717.

Yasuda, M., Hasunuma, Y., Adachi, H., Sekine, C., Sakanishi, T., Hashimoto, H., ... & Okumura, K. (1995). Expression and function of fibronectin binding integrins on rat mast cells. International immunology7(2), 251-258.

Wu, X., Mogford, J. E., Platts, S. H., Davis, G. E., Meininger, G. A., & Davis, M. J. (1998). Modulation of calcium current in arteriolar smooth muscle by αvβ3 and α5β1 integrin ligands. The Journal of cell biology143(1), 241-252.

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