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Anti-Mouse/Rat CD61 (Integrin beta 3) SAFIRE Purified



Catalog Number : 03712-25

Description

The 2C9.G3 monoclonal antibody specifically reacts with the mouse/rat CD61 molecule, known as the integrin beta 3 that forms the vitronectin receptor with CD51. The complex binds to other ligands such as fibrinogen, fibronectin, thrombospondin, and von WIllebrand factor. It is expressed by granulocytes, platelets, activated T cells, smooth muscle, and a subset of B cells.

Additional Information

Clone:
2C9.G3
Format:
SAFIRE Purified
Applications:
FC, FA
Reactivity:
Mouse, Rat
Isotype:
Armenian Hamster IgG
Research Interest: Adaptive Immunity, Angiogenesis
Cell Type: B Cells, T Cells
Preparation:
The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
References:

Vaillant, F., Asselin-Labat, M. L., Shackleton, M., Forrest, N. C., Lindeman, G. J., & Visvader, J. E. (2008). The mammary progenitor marker CD61/β3 integrin identifies cancer stem cells in mouse models of mammary tumorigenesis.Cancer research68(19), 7711-7717.

Yasuda, M., Hasunuma, Y., Adachi, H., Sekine, C., Sakanishi, T., Hashimoto, H., ... & Okumura, K. (1995). Expression and function of fibronectin binding integrins on rat mast cells. International immunology7(2), 251-258.

Wu, X., Mogford, J. E., Platts, S. H., Davis, G. E., Meininger, G. A., & Davis, M. J. (1998). Modulation of calcium current in arteriolar smooth muscle by αvβ3 and α5β1 integrin ligands. The Journal of cell biology143(1), 241-252.


Availability: In stock

Size Price Qty
50 ug
$100.00
100 ug
$175.00
Additional 2C9.G3 Formats
Cat.No. Format Starting From
03712-25SAFIRE Purified $ 100.00
03712-60PE $ 120.00