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Anti-Rat CD86 (B7-2) FITC



Catalog Number : 08913-50

Description

The 24F monoclonal antibody specifically reacts with CD86 (B7-2), a 90 kDA surface receptor present on antigen presenting cells and activated B and T cells. CD86 is a ligand for CD28 and CD152 and plays an essential role in B cell-T cell costimulatory interactions.

The 24F antibody is capable of blocking the co-stimulatory activity of CD86.

Additional Information

Clone:
24F
Format:
FITC
Applications:
FC
Reactivity:
Rat
Isotype:
Mouse IgG1, kappa
Research Interest: Innate Immunity
Cell Type: Dendritic Cells
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Maeda, K., Sato, T., Azuma, M., Yagita, H., & Okumura, K. (1997). Characterization of rat CD80 and CD86 by molecular cloning and mAb.International immunology9(7), 993-1000.

Damoiseaux, J. G., Yagita, H., Okumura, K., & van Breda Vriesman, P. J. (1998). Costimulatory molecules CD80 and CD86 in the rat; tissue distribution and expression by antigen-presenting cells. Journal of leukocyte biology64(6), 803-809.

BLUESTONE, J. (1995). New perspectives of CD28-B7-mediated T cell costimulation. Immunity2, 555-559.


Availability: In stock

Size Price Qty
50 ug
$100.00
100 ug
$190.00
Additional 24F Formats
Cat.No. Format Starting From
08913-50FITC $ 100.00