Anti-Mouse CD30 SAFIRE Purified
Additional mCD30.1 Formats
| Cat.No. | Format | Starting From |
|---|---|---|
| 02412-25 | SAFIRE Purified | $ 550.00 |
Catalog Number : 02412-25
description
The mCD301 monoclonal antibody specifically binds to mouse CD30, a member of the Tumor Necrosis Factor Receptor (TNFR) superfamily. It is expressed on activated T, B, NK, and monocyte cells. Its expression on activated T lymphocytes is regulated by cytokines and CD28. The ligand for CD30 is CD153. It has been suggested that the molecule plays a role in the protection against autoimmunity and the regulation of Th1 and Th2 cytokine secretion.
Additional Information
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Clone:
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mCD30.1
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Format:
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SAFIRE Purified
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Applications:
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FC, FA
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Reactivity:
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Mouse
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Isotype:
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Armenian Hamster IgG
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| Research Interest: | Apoptosis |
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| Cell Type: | B Cells, T Cells, NK and NKT Cells, Macrophage / Monocyte |
| Application: | FC, FA |
| Clone: | mCD30.1 |
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Preparation:
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The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
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Formulation:
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Phosphate-buffered aqueous solution, ph7.2.
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References:
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Siegmund, T., Armitage, N., Wicker, L. S., Peterson, L. B., Todd, J. A., & Lyons, P. A. (2000). Analysis of the mouse CD30 gene: a candidate for the NOD mouse type 1 diabetes locus Idd9. 2. Diabetes, 49(9), 1612-1616. Falini, B., Pileri, S., Pizzolo, G., Dürkop, H., Flenghi, L., Stirpe, F., ... & Stein, H. (1995). CD30 (Ki-1) molecule: a new cytokine receptor of the tumor necrosis factor receptor superfamily as a tool for diagnosis and immunotherapy. BLOOD-NEW YORK-, 85, 1-1. Heath, W. R., Kurts, C., Caminschi, I., Carbone, F. R., & Miller, J. F. (1999). CD 30 prevents T‐cell responses to non‐lymphoid tissues. Immunological reviews, 169(1), 23-29.
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