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Anti-Mouse CD30 SAFIRE Purified



Catalog Number : 02412-25

Description

The mCD301 monoclonal antibody specifically binds to mouse CD30, a member of the Tumor Necrosis Factor Receptor (TNFR) superfamily. It is expressed on activated T, B, NK, and monocyte cells. Its expression on activated T lymphocytes is regulated by cytokines and CD28. The ligand for CD30 is CD153. It has been suggested that the molecule plays a role in the protection against autoimmunity and the regulation of Th1 and Th2 cytokine secretion.

Additional Information

Clone:
mCD30.1
Format:
SAFIRE Purified
Applications:
FC, FA
Reactivity:
Mouse
Isotype:
Armenian Hamster IgG
Research Interest: Apoptosis
Cell Type: B Cells, T Cells, NK and NKT Cells, Monocytes and Macrophages
Preparation:
The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
References:

Siegmund, T., Armitage, N., Wicker, L. S., Peterson, L. B., Todd, J. A., & Lyons, P. A. (2000). Analysis of the mouse CD30 gene: a candidate for the NOD mouse type 1 diabetes locus Idd9. 2. Diabetes49(9), 1612-1616.

Falini, B., Pileri, S., Pizzolo, G., Dürkop, H., Flenghi, L., Stirpe, F., ... & Stein, H. (1995). CD30 (Ki-1) molecule: a new cytokine receptor of the tumor necrosis factor receptor superfamily as a tool for diagnosis and immunotherapy. BLOOD-NEW YORK-85, 1-1.

Heath, W. R., Kurts, C., Caminschi, I., Carbone, F. R., & Miller, J. F. (1999). CD 30 prevents T‐cell responses to non‐lymphoid tissues. Immunological reviews169(1), 23-29.

 


Availability: In stock

Size Price Qty
50 ug
$100.00
100 ug
$175.00
500 ug
$330.00
Additional mCD30.1 Formats
Cat.No. Format Starting From
02412-25SAFIRE Purified $ 100.00