Anti-Human CD134 (OX40) APC
Catalog Number : 16411-80
description
The ACT35 monoclonal antibody reacts with human CD134 (OX40), a type I transmembrane glycoprotein in the TNF superfamily. It is expressed on activated T lymphocytes and enhances cell survival.
Additional Information
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Clone:
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ACT35
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Format:
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APC
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Applications:
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FC
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Reactivity:
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Human
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Isotype:
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Mouse IgG1
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| Research Interest: | Adaptive Immunity |
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| Cell Type: | T Cells |
| Application: | FC |
| Clone: | ACT35 |
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Preparation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Croft, M. (2009). Control of immunity by the TNFR-related molecule OX40 (CD134). Annual review of immunology, 28, 57-78. Jones, D., Fletcher, C. D., Pulford, K., Shahsafaei, A., & Dorfman, D. M. (1999). The T-cell activation markers CD30 and OX40/CD134 are expressed in nonoverlapping subsets of peripheral T-cell lymphoma. Blood, 93(10), 3487-3493. Xiaoyan, Z., Pirskanen, R., Malmstrom, V., & Lefvert, A. K. (2006). Expression of OX40 (CD134) on CD4+ T‐cells from patients with myasthenia gravis. Clinical & Experimental Immunology, 143(1), 110-116. |