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Anti-Human CD161 PerCP-Cyanine5.5



Catalog Number : 13711-70

Description

The HP-3G10 monoclonal antibody specifically binds to an 80 kDa homodimer type II membrane glycoprotein from the C-type lectin superfamily, known as the human CD161 or NKR-P1A. CD161 is expressed on most natural killer cells, subsets of CD4+ and CD8+ T lymphocytes, γδ TCR T lymphocytes, a subset of CD3+ thymocytes, and especially on CD45RO+ T lymphocytes. Reports indicate that it may serve as a specific receptor for some natural killer cell targets and a possible stimulatory role.

Additional Information

Clone
HP-3G10
Format:
PerCP-Cyanine5.5
Applications
FC
Reactivity
Human
Isotype:
Mouse IgG1, kappa
Research Interest: Adaptive Immunity, Innate Immunity
Cell Type: NK and NKT Cells, T Cells, Th17 cells
Preperation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Márquez, C., Trigueros, C., Franco, J. M., Ramiro, A. R., Carrasco, Y. R., López-Botet, M., & Toribio, M. L. (1998). Identification of a common developmental pathway for thymic natural killer cells and dendritic cells. Blood,91(8), 2760-2771.

Cosmi, L., De Palma, R., Santarlasci, V., Maggi, L., Capone, M., Frosali, F., ... & Annunziato, F. (2008). Human interleukin 17–producing cells originate from a CD161+ CD4+ T cell precursor. The Journal of experimental medicine205(8), 1903-1916.

Exley, M., Porcelli, S., Furman, M., Garcia, J., & Balk, S. (1998). CD161 (NKR-P1A) costimulation of CD1d-dependent activation of human T cells expressing invariant Vα24JαQ T cell receptor α chains. The Journal of experimental medicine188(5), 867-876.


Availability: In stock

Size Price Qty
25 tests
$130.00
100 tests
$295.00
Additional HP-3G10 Formats
Cat.No. Format Starting From
13711-60PE $ 95.00
13711-70PerCP-Cyanine5.5 $ 130.00
13711-40BG Violet 450 $ 105.00
13711-20Purified $ 105.00
13711-50FITC $ 95.00
13711-80APC $ 115.00