Anti-Human CD161 APC

Catalog Number : 13711-80

Description

The HP-3G10 monoclonal antibody specifically binds to an 80 kDa homodimer type II membrane glycoprotein from the C-type lectin superfamily, known as the human CD161 or NKR-P1A. CD161 is expressed on most natural killer cells, subsets of CD4+ and CD8+ T lymphocytes, γδ TCR T lymphocytes, a subset of CD3+ thymocytes, and especially on CD45RO+ T lymphocytes. Reports indicate that it may serve as a specific receptor for some natural killer cell targets and a possible stimulatory role.

Additional Information

Clone:	HP-3G10
Format:	APC
Applications:	FC
Reactivity:	Human
Isotype:	Mouse IgG1, kappa
Research Interest:	Adaptive Immunity, Innate Immunity
Cell Type:	NK and NKT Cells, T Cells, Th17 cells
Protein Cross Reactivity:	Chimpanzee, Baboon, Rhesus
Preparation:	The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:	Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:	Márquez, C., Trigueros, C., Franco, J. M., Ramiro, A. R., Carrasco, Y. R., López-Botet, M., & Toribio, M. L. (1998). Identification of a common developmental pathway for thymic natural killer cells and dendritic cells. Blood,91(8), 2760-2771. Cosmi, L., De Palma, R., Santarlasci, V., Maggi, L., Capone, M., Frosali, F., ... & Annunziato, F. (2008). Human interleukin 17–producing cells originate from a CD161+ CD4+ T cell precursor. The Journal of experimental medicine, 205(8), 1903-1916. Exley, M., Porcelli, S., Furman, M., Garcia, J., & Balk, S. (1998). CD161 (NKR-P1A) costimulation of CD1d-dependent activation of human T cells expressing invariant Vα24JαQ T cell receptor α chains. The Journal of experimental medicine, 188(5), 867-876.

Availability: In stock

Size	Price	Qty
25 tests	$115.00
100 tests	$240.00

Additional HP-3G10 Formats

Cat.No.	Format	Starting From
13711-60	PE	$ 95.00
13711-70	PerCP-Cyanine5.5	$ 130.00
13711-40	BG Violet 450	$ 105.00
13711-20	Purified	$ 105.00
13711-50	FITC	$ 95.00
13711-80	APC	$ 115.00