bpV(HOpic)
Catalog Number : 7222604
description
bpV(HOpic) is a protein tyrosine phosphatases (PTPs) and a potent PTEN inhibitor. It is reported to function as an insulin mimetic and activate the insulin receptor kinase (IRK).
Additional Information
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Applications:
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FA
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Synonyms:
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Bisperoxovanadium(HOpic), bpV (HOpic)
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Formulation:
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Crystalline solid
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Chemical Name:
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(5-hydroxy-2-pyridinecarboxylato-κN1,κO2)oxodiperoxy-vanadate(2-)
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Molecular Formula:
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K2[VO(O2)2C6H4NO3] |
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Molecular Weight: |
347.2
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CAS Number
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722494-26-0
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Purity:
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≥95%
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Storage Conditions:
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Product should be kept at -20°C.
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References:
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Liao, J., Marumoto, T., Yamaguchi, S., Okano, S., Takeda, N., Sakamoto, C., ... & Okada, M. (2013). Inhibition of PTEN tumor suppressor promotes the generation of induced pluripotent stem cells. Molecular therapy, 21(6), 1242-1250. Dimchev, G. A., Al-Shanti, N., & Stewart, C. E. (2013). Phospho-tyrosine phosphatase inhibitor Bpv (Hopic) enhances C2C12 myoblast migration in vitro. Requirement of PI3K/AKT and MAPK/ERK pathways. Journal of muscle research and cell motility, 34(2), 125-136. Adhikari, D., Gorre, N., Risal, S., Zhao, Z., Zhang, H., Shen, Y., & Liu, K. (2012). The safe use of a PTEN inhibitor for the activation of dormant mouse primordial follicles and generation of fertilizable eggs. PLoS one, 7(6), e39034. |