Anti-Mouse CD172a (SIRP alpha) SAFIRE Purified

Grouped product items
Size Price Qty
50ug
$165.00
500ug
$385.00

Additional P84 Formats

Cat.No. Format Starting From
14812-25 SAFIRE Purified $ 165.00
Catalog Number : 14812-25

description

The P84 monoclonal antibody specifically reacts with mouse CD172a, a type I transmembrane protein otherwise known as the signal-regulatory protein alpha. It is an adhesion molecules expressed on dendritic cells, monocytes, macrophages, and neuronal tissue. It is reported to be involved in regulating the phagocytic activity of macrophages and mediating neural synaptic activity. The P84 antibody is reported to have neutralizing capability.

Additional Information

Clone:
P84
Format:
SAFIRE Purified
Applications:
FC, FA
Reactivity:
Mouse
Isotype:
Rat IgG1, kappa
Cell Type: Dendritic Cells, Macrophage / Monocyte
Application: FC, FA
Clone: P84
Preparation:
The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography.
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
References:

Liu, K., Victora, G. D., Schwickert, T. A., Guermonprez, P., Meredith, M. M., Yao, K., ... & Nussenzweig, M. (2009). In vivo analysis of dendritic cell development and homeostasis. Science324(5925), 392-397.

Mi, Z. P., Jiang, P., Weng, W. L., Lindberg, F. P., Narayanan, V., & Lagenaur, C. F. (2000). Expression of a synapse‐associated membrane protein, P84/SHPS‐1, and its ligand, IAP/CD47, in mouse retina. Journal of Comparative Neurology416(3), 335-344.

Chuang, W., & Lagenaur, C. F. (1990). Central nervous system antigen P84 can serve as a substrate for neurite outgrowth. Developmental biology137(2), 219-232.

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