Anti-Rat CD28 PE

Grouped product items
Size Price Qty
50 ug
$100.00
200 ug
$310.00

Additional JJ319 Formats

Cat.No. Format Starting From
10313-25 SAFIRE Purified $ 110.00
10313-60 PE $ 100.00
Catalog Number : 10313-60

description

The JJ319 monoclonal antibody specifically reacts with rat CD28, a 44 kDa glycoprotein member of the immunoglobulin superfamily. CD28 is expressed on alpha/beta TCR+ T cells, some gamma/delta TCR+ T cells and a subset of NK cells. CD28 is a costimulatory receptor required for T cell activation. Its ligands are CD80 (B7-1) and CD86 (B7-2).

Additional Information

Clone:
JJ319
Format:
PE
Applications:
FC
Reactivity:
Rat
Isotype:
Mouse IgG1
Research Interest: Adaptive Immunity
Cell Type: T Cells
Application: FC
Clone: JJ319
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Tacke, M., Clark, G. J., Dallman, M. J., & Hünig, T. (1995). Cellular distribution and costimulatory function of rat CD28. Regulated expression during thymocyte maturation and induction of cyclosporin A sensitivity of costimulated T cell responses by phorbol ester. The Journal of Immunology154(10), 5121-5127.

Tacke, M., Hanke, G., Hanke, T. H T. (1997). CD28‐mediated induction of proliferation in resting T cells in vitro and in vivo without engagement of the T cell receptor: Evidence for functionally distinct forms of CD28.European journal of immunology27(1), 239-247.

Bluestone, J. A. (1995). New perspectives of CD28-B7-mediated T cell costimulation. Immunity2(6), 555-559.

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