Anti-Human IL-4 APC
Catalog Number : 81121-80
description
The MP4-25D2 monoclonal antibody specifically reacts with human Interleukin-4 (IL-4), expressed by the activated T cells and mast cells. IL-4 is species-specific and stimulates the proliferation and differentiation of B lymphocytes. It upregulates the expression of IgE receptors and class II MHC antigen. The MP4-25D2 is a neutralizing antibody and is reported to be cross-reactive with rhesus monkeys.
Additional Information
Clone: | MP4-25D2 |
Format: | APC |
Applications: | FC |
Reactivity: | Human |
Isotype: | Rat IgG1, kappa |
| Research Interest: | Innate Immunity, Adaptive Immunity, Cytokines & Growth Factors |
|---|---|
| Cell Type: | T Cells |
| Application: | FC |
| Clone: | MP4-25D2 |
Preparation: | The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product. |
Formulation: | Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2. |
References: | Abrams, J. S., Roncarolo, M. G., Yssel, H., Andersson, U., Gleich, G. J., & Silver, J. E. (1992). Strategies of anti‐cytokine monoclonal antibody development: immunoassay of IL‐10 and IL‐5 in clinical samples.Immunological reviews, 127(1), 5-24. Chrétien, I., Van Kimmenade, A., Pearce, M. K., Banchereau, J., & Abrams, J. S. (1989). Development of polyclonal and monoclonal antibodies for immunoassay and neutralization of human interleukin-4. Journal of immunological methods, 117(1), 67-81. Jung, T., Schauer, U., Rieger, C., Wagner, K., Einsle, K., Neumann, C., & Heusser, C. (1995). Interleukin‐4 and interleukin‐5 are rarely co‐expressed by human T cells. European journal of immunology, 25(8), 2413-2416. |