Anti-Human IL-4 APC

Grouped product items
SizePrice Qty
25 tests
$80.00
100 tests
$215.00

Additional MP4-25D2 Formats

Cat.No.FormatStarting From
81121-25SAFIRE Purified$ 85.00
81121-60PE$ 80.00
81121-80APC$ 80.00
Catalog Number : 81121-80

description

The MP4-25D2 monoclonal antibody specifically reacts with human Interleukin-4 (IL-4), expressed by the activated T cells and mast cells. IL-4 is species-specific and stimulates the proliferation and differentiation of B lymphocytes. It upregulates the expression of IgE receptors and class II MHC antigen. The MP4-25D2 is a neutralizing antibody and is reported to be cross-reactive with rhesus monkeys.

Additional Information

Clone:
MP4-25D2
Format:
APC
Applications:
FC
Reactivity:
Human
Isotype:
Rat IgG1, kappa
Research Interest:Innate Immunity, Adaptive Immunity, Cytokines & Growth Factors
Cell Type:T Cells
Application:FC
Clone:MP4-25D2
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Abrams, J. S., Roncarolo, M. G., Yssel, H., Andersson, U., Gleich, G. J., & Silver, J. E. (1992). Strategies of anti‐cytokine monoclonal antibody development: immunoassay of IL‐10 and IL‐5 in clinical samples.Immunological reviews127(1), 5-24.

Chrétien, I., Van Kimmenade, A., Pearce, M. K., Banchereau, J., & Abrams, J. S. (1989). Development of polyclonal and monoclonal antibodies for immunoassay and neutralization of human interleukin-4. Journal of immunological methods117(1), 67-81.

Jung, T., Schauer, U., Rieger, C., Wagner, K., Einsle, K., Neumann, C., & Heusser, C. (1995). Interleukin‐4 and interleukin‐5 are rarely co‐expressed by human T cells. European journal of immunology25(8), 2413-2416.

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