Anti-Human CD4 Biotin

Grouped product items
SizePrice Qty
25 ug
$65.00
100 ug
$145.00

Additional OKT4 Formats

Cat.No.FormatStarting From
06111-20Purified$ 65.00
06111-50FITC$ 40.00
06111-40BG Violet 450$ 95.00
06111-80APC$ 70.00
06111-60PE$ 55.00
06111-70PerCP-Cyanine5.5 $ 80.00
06111-30Biotin$ 65.00
Catalog Number : 06111-30

description

The OKT4 monoclonal antibody specifically binds to the CD4 receptor for the human immunodeficiency virus (HIV). CD4 is a 59 kDa single-chain transmembrane glycoprotein that expressed on the surface of most of the thymocytes, T-helper cells, and in low levels on monocytes and macrophages. CD4 is a co-receptor in the antigen-induced T cell activation (together with the MHC class II). The OKT4 and the RPA-T4 monoclonal antibodies recognize different epitopes of CD4 and they do not exhibit cross-block binding.

Additional Information

Clone:
OKT4
Format:
Biotin
Applications:
FC
Reactivity:
Human
Isotype:
Mouse IgG2b, kappa
Research Interest:Adaptive Immunity
Cell Type:T Cells, Macrophage / Monocyte, T Regulatory Cells
Application:FC
Clone:OKT4
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Reinherz, E. L., Kung, P. C., Goldstein, G., & Schlossman, S. F. (1979). Separation of functional subsets of human T cells by a monoclonal antibody.Proceedings of the National Academy of Sciences76(8), 4061-4065.

 Knapp W (1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

Bour, S. T. E. P. H. A. N. E., Boulerice, F. R. A. N. C. O. I. S., & Wainberg, M. A. (1991). Inhibition of gp160 and CD4 maturation in U937 cells after both defective and productive infections by human immunodeficiency virus type 1.Journal of virology65(12), 6387-6396.

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