Anti-Mouse CD140a (PDGF Receptor a) APC

Grouped product items
SizePrice Qty
50 ug
$165.00

Additional APA5 Formats

Cat.No.FormatStarting From
12512-30Biotin$ 90.00
12512-25SAFIRE Purified$ 220.00
12512-80APC$ 165.00
Catalog Number : 12512-80

description

The APA5 monoclonal antibody specifically binds to the mouse CD140a molecule, otherwise known as the Platelet-Derived Growth Factor (PDGF) Receptor alpha chain. CD140a is a receptor tyrosine kinase expressed on embryonic tissues and adult mesenchymal-derived cells. It binds to PDGF A and B chains and is reported to be involved with wound healing and exhibits chemo-attractant properties. The APA5 antibody blocks the binding of PDGF-AA to the PDGF receptor.

Additional Information

Clone:
APA5
Format:
APC
Applications:
FC
Reactivity:
Mouse
Isotype:
Rat IgG2a, kappa
Research Interest:Stem Cell Research
Cell Type:Stem Cells
Application:FC
Clone:APA5
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted biotin was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Fruttiger, M., Calver, A. R., Krüger, W. H., Mudhar, H. S., Michalovich, D., Takakura, N., ... & Richardson, W. D. (1996). PDGF mediates a neuron–astrocyte interaction in the developing retina. Neuron17(6), 1117-1131.

Takakura, N., Yoshida, H., Ogura, Y., Kataoka, H., Nishikawa, S., & Nishikawa, S. I. (1997). PDGFRα expression during mouse embryogenesis: immunolocalization analyzed by whole-mount immunohistostaining using the monoclonal anti-mouse PDGFRα antibody APA5. Journal of Histochemistry & Cytochemistry45(6), 883-893.

Takakura, N., Yoshida, H., Kunisada, T., Nishikawa, S., & Nishikawa, S. I. (1996). Involvement of Platelet-Derived Growth Factor Receptor-&agr; in Hair Canal Formation. Journal of investigative dermatology107(5), 770-777.

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