Anti-Human CD35 (CR1) APC
Catalog Number : 07411-80
description
The E11 monoclonal antibody specifically binds to human CD35, a type I glycoprotein also known as Complement Receptor type 1 (CR1). It is expressed on B cells, monocytes, granulocytes, subsets of NK cells, substs of T cells, follicular dendritic cells, and erythrocytes. CD35 is reported to inhibit T-cell proliferation and mediate phagocytosis by monocytes and granulocytes.
Additional Information
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Clone:
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E11
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Format:
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APC
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Applications:
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FC
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Reactivity:
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Human
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Isotype:
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Mouse IgG1, kappa
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| Research Interest: | Adaptive Immunity, Innate Immunity |
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| Cell Type: | B Cells, Macrophage / Monocyte |
| Application: | FC |
| Clone: | E11 |
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Preparation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Barclay, A. N., Brown, M. H., Law, S. A. K. A., McKnight, A. J., Tomlinson, M. G., & van der Merwe, P. A. (1997). The leucocyte antigen factsbook. Academic Press. Dougherty, G. J., Selvendran, Y., Murdoch, S., Palmer, D. G., & Hogg, N. (1987). The human mononuclear phagocyte high‐affinity Fc receptor, FcRI, defined by a monoclonal antibody, 10.1. European journal of immunology, 17(10), 1453-1459. Hogg, N., Ross, G. D., Jones, D. B., Slusarenko, M., Walport, M. J., & Lachmann, P. J. (1984). Identification of an anti‐monocyte monoclonal antibody that is specific for membrane complement receptor type one (CR1). European journal of immunology, 14(3), 236-243. |