Anti-Human CD3 APC
Additional OKT3 Formats
Cat.No. | Format | Starting From |
---|---|---|
05121-20 | Purified | $ 115.00 |
05121-25 | SAFIRE Purified | $ 160.00 |
05121-40 | BG Violet 450 | $ 95.00 |
05121-60 | PE | $ 50.00 |
05121-80 | APC | $ 65.00 |
05121-50 | FITC | $ 40.00 |
05121-70 | PerCP-Cyanine5.5 | $ 135.00 |
05121-77 | PE-Cyanine7 | $ 95.00 |
description
The OKT3 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains γ, δ, and ε chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction.
The OKT3 antibody is an immunosuppressive, which has proven to be an effective therapeutic agent in liver, heart, and renal allograft rejection.
Additional Information
Clone:
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OKT3
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Format:
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APC
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Applications:
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FC
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Reactivity:
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Human
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Isotype:
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Mouse IgG2a, kappa
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Research Interest: | Adaptive Immunity |
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Cell Type: | NK and NKT Cells, T Cells, T Regulatory Cells, Th17 cells |
Application: | FC |
Clone: | OKT3 |
Preparation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Schlossman, S., L. Bloumsell, et al. eds (1995). Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York Knapp W (1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989. Adair, J. R., Athwal, D. S., Bodmer, M. W., Bright, S. M., Collins, A. M., Pulito, V. L., ... & Jolliffe, L. K. (1994). Humanization of the murine anti-human CD3 monoclonal antibody OKT3. Human Antibodies, 5(1), 41-47. |