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Anti-Mouse IL-2 APC



Catalog Number : 86412-80

Description

The JES6-5H4 antibody specifically binds to mouse IL-2, a 17 kDa immunoregulatory cytokine and growth factor for T and B lymphocytes, NK cells, monocytes, and macrophages. IL-2 induces the cytotoxic operations of NK cells, activates B cells, and plays a role in the differentiation of T cells.

JES6-5H4 seems to have a neutralizing effect on interleukin-2.

Additional Information

Clone
JES6-5H4
Format:
APC
Applications
FC
Reactivity
Mouse
Isotype:
Rat IgG2b, kappa
Research Interest: Adaptive Immunity
Cell Type: T Cells, Treg cells
Preperation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Sander, B., Höidén, I., Andersson, U., Möller, E., & Abrams, J. S. (1993). Similar frequencies and kinetics of cytokine producing cells in murine peripheral blood and spleen: Cytokine detection by immunoassay and intracellular immunostraining. Journal of immunological methods, 166(2), 201-214.

Abrams, J. S., Roncarolo, M. G., Yssel, H., Andersson, U., Gleich, G. J., & Silver, J. E. (1992). Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples. Immunological reviews, 127(1), 5-24.

Abrams, J. S. (1995). Immunoenzymetric assay of mouse and human cytokines using NIP-labeled anti-cytokine antibodies (pp. 6-20). John Wiley & Sons, Inc..


Availability: In stock

Size Price Qty
25 μg
$80.00
100 μg
$215.00
Additional JES6-5H4 Formats
Cat.No. Format Starting From
86412-60PE $ 70.00
86412-30Biotin $ 60.00
86412-80APC $ 80.00