Anti-Mouse IL-2 APC
description
The JES6-5H4 antibody specifically binds to mouse IL-2, a 17 kDa immunoregulatory cytokine and growth factor for T and B lymphocytes, NK cells, monocytes, and macrophages. IL-2 induces the cytotoxic operations of NK cells, activates B cells, and plays a role in the differentiation of T cells.
JES6-5H4 seems to have a neutralizing effect on interleukin-2.
Additional Information
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Clone:
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JES6-5H4
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Format:
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APC
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Applications:
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FC
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Reactivity:
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Mouse
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Isotype:
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Rat IgG2b, kappa
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| Research Interest: | Adaptive Immunity |
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| Cell Type: | T Cells, T Regulatory Cells |
| Application: | FC |
| Clone: | JES6-5H4 |
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Preparation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Sander, B., Höidén, I., Andersson, U., Möller, E., & Abrams, J. S. (1993). Similar frequencies and kinetics of cytokine producing cells in murine peripheral blood and spleen: Cytokine detection by immunoassay and intracellular immunostraining. Journal of immunological methods, 166(2), 201-214. Abrams, J. S., Roncarolo, M. G., Yssel, H., Andersson, U., Gleich, G. J., & Silver, J. E. (1992). Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples. Immunological reviews, 127(1), 5-24. Abrams, J. S. (1995). Immunoenzymetric assay of mouse and human cytokines using NIP-labeled anti-cytokine antibodies (pp. 6-20). John Wiley & Sons, Inc.. |