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Anti-Mouse CD115 (CSF-1R) SAFIRE Purified

Catalog Number : 17212-25


The AFS98 monoclonal antibody specifically reacts with the mouse CD115 molecule, a 150 kDa receptor for the colony stimulating factor (CSF-1) or macrophage CFS (M-CFS), expressed by some epithelial cells, monocytes, osteoclasts, and macrophages. The colony stimulating factor-1 regulates the proliferation and the differentiation of the monocytic lineage cells.

The AFS98 antibody can be used to identify myeloid lineage cells.

Additional Information

SAFIRE Purified
Rat IgG2a, kappa
Research Interest: Innate Immunity, Angiogenesis
Cell Type: Monocytes and Macrophages
The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Phosphate-buffered aqueous solution, ph7.2.

Murayama, T., Yokode, M., Kataoka, H., Imabayashi, T., Yoshida, H., Sano, H., ... & Kita, T. (1999). Intraperitoneal administration of anti–c-fms monoclonal antibody prevents initial events of atherogenesis but does not reduce the size of advanced lesions in apolipoprotein E–deficient mice. Circulation99(13), 1740-1746.

Sudo, T., Nishikawa, S., Ogawa, M., Kataoka, H., Ohno, N., Izawa, A., & Hayashi, S. (1995). Functional hierarchy of c-kit and c-fms in intramarrow production of CFU-M. Oncogene11(12), 2469-2476.

Yoshino, M., Yamazaki, H., Yoshida, H., Niida, S., Nishikawa, S. I., Ryoke, K., ... & Hayashi, S. I. (2003). Reduction of osteoclasts in a critical embryonic period is essential for inhibition of mouse tooth eruption. Journal of Bone and Mineral Research18(1), 108-116.

Availability: In stock

Size Price Qty
100 μg
500 μg
Additional AFS98 Formats
Cat.No. Format Starting From
17212-25SAFIRE Purified $ 195.00
17212-50FITC $ 90.00
17212-80APC $ 80.00
17212-60PE $ 90.00