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Anti-Mouse CD115 (CSF-1R) FITC

Catalog Number : 17212-50


The AFS98 monoclonal antibody specifically reacts with the mouse CD115 molecule, a 150 kDa receptor for the colony stimulating factor (CSF-1) or macrophage CFS (M-CFS), expressed by some epithelial cells, monocytes, osteoclasts, and macrophages. The colony stimulating factor-1 regulates the proliferation and the differentiation of the monocytic lineage cells.

The AFS98 antibody can be used to identify myeloid lineage cells.

Additional Information

Mouse, Rat
Rat IgG2a, kappa
Research Interest: Innate Immunity, Angiogenesis
Cell Type: Monocytes and Macrophages
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Murayama, T., Yokode, M., Kataoka, H., Imabayashi, T., Yoshida, H., Sano, H., ... & Kita, T. (1999). Intraperitoneal administration of anti–c-fms monoclonal antibody prevents initial events of atherogenesis but does not reduce the size of advanced lesions in apolipoprotein E–deficient mice. Circulation99(13), 1740-1746.

Sudo, T., Nishikawa, S., Ogawa, M., Kataoka, H., Ohno, N., Izawa, A., & Hayashi, S. (1995). Functional hierarchy of c-kit and c-fms in intramarrow production of CFU-M. Oncogene11(12), 2469-2476.

Yoshino, M., Yamazaki, H., Yoshida, H., Niida, S., Nishikawa, S. I., Ryoke, K., ... & Hayashi, S. I. (2003). Reduction of osteoclasts in a critical embryonic period is essential for inhibition of mouse tooth eruption. Journal of Bone and Mineral Research18(1), 108-116.

Availability: In stock

Size Price Qty
25 μg
100 μg
Additional AFS98 Formats
Cat.No. Format Starting From
17212-25SAFIRE Purified $ 195.00
17212-50FITC $ 90.00
17212-80APC $ 80.00
17212-60PE $ 90.00