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Anti-Human CD3 BG Violet 450



Catalog Number : 05131-40

Description

The UCHT1 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains γ, δ, and ε chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction.

Unlike HIT3a, another specific antibody of CD3, the UCHT1 antibody can stain both the surface and intracellular CD3ε. The immobilized UCHT1 can cross-link with the TCR complex, enhancing cellular activation and proliferation.

BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450nm.

Additional Information

Clone
UCHT1
Format:
BG Violet 450
Applications
FC
Reactivity
Human
Isotype:
Mouse IgG1, kappa
Research Interest: Adaptive Immunity
Cell Type: NK and NKT Cells, T Cells, Treg cells, Th17 cells
Preperation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Knapp W (1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

McMichael, A. J. (1987). Leucocyte typing III. Oxford University Press, Oxford. Norton AJ, Isaacson PG (1985)

Beverley, P. C., & Callard, R. E. (1981). Distinctive functional characteristics of human T lymphocytes defined by E rosetting or a monoclonal anti-T cell antibody. European journal of immunology11(4), 329-334.


Availability: In stock

Size Price Qty
25 tests
$85.00
100 tests
$205.00
Additional UCHT1 Formats
Cat.No. Format Starting From
05131-20Purified $ 75.00
05131-25SAFIRE Purified $ 150.00
05131-87APC-Cyanine7 $ 115.00
05131-50FITC $ 40.00
05131-77PE-Cyanine7 $ 115.00
05131-40BG Violet 450 $ 85.00
05131-80APC $ 65.00
05131-70PerCP-Cyanine5.5 $ 135.00
05131-30Biotin $ 65.00
05131-60PE $ 55.00
05131-65PE-Cyanine5 $ 120.00