Wnt-C59
description
Additional Information
Applications:
|
FA
|
Synonyms:
|
WNTC59
|
Formulation:
|
Crystalline solid
|
Chemical Name:
|
2-[4-(2-methylpyridin-4-yl)phenyl]-N-(4-pyridin-3-ylphenyl)acetamide
|
Molecular Formula:
|
C25H21N3O |
Molecular Weight: |
379.5
|
CAS Number
|
1243243-89-1
|
Purity:
|
≥98%
|
Storage Conditions:
|
Product should be kept at -20°C.
|
References:
|
Cheng, Y., Phoon, Y. P., Jin, X., Chong, S. Y. S., Ip, J. C. Y., Wong, B. W. Y., & Lung, M. L. (2015). Wnt-C59 arrests stemness and suppresses growth of nasopharyngeal carcinoma in mice by inhibiting the Wnt pathway in the tumor microenvironment. Oncotarget, 6(16), 14428. Proffitt, K. D., Madan, B., Ke, Z., Pendharkar, V., Ding, L., Lee, M. A., ... & Virshup, D. M. (2013). Pharmacological inhibition of the Wnt acyltransferase PORCN prevents growth of WNT-driven mammary cancer. Cancer research, 73(2), 502-507. Kadari, A., Mekala, S., Wagner, N., Malan, D., Köth, J., Doll, K., ... & Sasse, P. (2015). Robust generation of cardiomyocytes from human iPS cells requires precise modulation of BMP and WNT signaling. Stem Cell Reviews and Reports, 11(4), 560-569. |