Stauprimide
Catalog Number : 1549658
description
Stauprimide is a staurosporine that interacts with the NME2 (PUF) transcription factor to down-regulate c-Myc expression. This biological effect primes cells for further cellular differentiation.
Additional Information
Applications:
|
FA
|
Synonyms:
|
N-Benzoyl-7-oxostaurosporine, AKOS024457783
|
Formulation:
|
Crystalline solid
|
Chemical Name:
|
N-[(2S,3R,4R,6R)-3-Methoxy-2-methyl-16,18-dioxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-4-yl]-N-methylbenzamide
|
Molecular Formula:
|
C35H28N4O5 |
Molecular Weight: |
584.6
|
CAS Number
|
154589-96-5
|
Purity:
|
≥98%
|
Storage Conditions:
|
Product should be kept at -20°C.
|
References:
|
Zaret, K. S. (2009). Using small molecules to great effect in stem cell differentiation. Cell stem cell, 4(5), 373-374. Zhu, S., Wurdak, H., & Schultz, P. G. (2010). Directed embryonic stem cell differentiation with small molecules. Future medicinal chemistry, 2(6), 965-973. Li, W., & Ding, S. (2010). Small molecules that modulate embryonic stem cell fate and somatic cell reprogramming. Trends in pharmacological sciences,31(1), 36-45. |