IBMX

Grouped product items
SizePrice Qty
100mg
$35.00
1g
$145.00
Catalog Number : 2885842

description

IBMX is a general inhibitor of cyclic nucleotide phosphodiesterases, increasing the level of intracellular cAMP. It is used to increase cell differentiation, decrease proliferation, and induce apoptosis. IBMX is reported to inhibit TNF-alpha, reduce inflammation, and activate PKA.
product image

Additional Information

Applications:
FA
Synonyms:
1-Methyl-3-isobutylxanthine, 3-Isobutyl-1-methylxanthine, Isobutyltheophylline
Formulation:
Crystalline solid
Chemical Name:
1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione
Molecular Formula:

C10H14N4O2

Molecular Weight:
222.3
CAS Number
28822-58-4
Purity:
≥98%
Storage Conditions:
Product should be kept at -20°C.
References:

Usachev, Y., & Verkhratsky, A. (1995). IBMX induces calcium release from intracellular stores in rat sensory neurones. Cell calcium17(3), 197-206.

Tio, M., Tan, K. H., Lee, W., Wang, T. T., & Udolph, G. (2010). Roles of db-cAMP, IBMX and RA in aspects of neural differentiation of cord blood derived mesenchymal-like stem cells. PLoS One5(2), e9398.

Hube, F., Lee, Y. M., Röhrig, K., & Hauner, H. (1999). The phosphodiesterase inhibitor IBMX suppresses TNF-alpha expression in human adipocyte precursor cells: a possible explanation for its adipogenic effect. Hormone and metabolic research= Hormon-und Stoffwechselforschung= Hormones et metabolisme,31(6), 359-362.

© BioGems International, Inc. All rights reserved.