DL-AP5

Grouped product items
SizePrice Qty
10mg
$65.00
50mg
$270.00
Catalog Number : 7633136

description

DL-AP5 is the racemic version of AP5, a selective N-methyl-D-aspartate (NMDA) receptor antagonist that binds at glutamate site. DL-AP5 exhibits less potent NMDA receptor antagonist activity than the D-AP5 version and is used in the research of synaptic plasticity.
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Additional Information

Applications:
FA
Synonyms:
APV acid, 2-Amino-5-phosphovaleric acid,
Formulation:
Crystalline solid
Chemical Name:
2-amino-5-phosphonopentanoic acid
Molecular Formula:

C5H12NO5P

Molecular Weight:
197.1
CAS Number
76326-31-3
Purity:
≥95%
Storage Conditions:
Product should be kept at -20°C.
References:

Steele, R. J., & Morris, R. G. M. (1999). Delay‐dependent impairment of a matching‐to‐place task with chronic and intrahippocampal infusion of the NMDA‐antagonist D‐AP5. Hippocampus9(2), 118-136.

Morris, R. G. (1989). Synaptic plasticity and learning: selective impairment of learning rats and blockade of long-term potentiation in vivo by the N-methyl-D-aspartate receptor antagonist AP5. The Journal of neuroscience,9(9), 3040-3057.

Davies, J., & Watkins, J. C. (1982). Actions of D and L forms of 2-amino-5-phosphonovalerate and 2-amino-4-phosphonobutyrate in the cat spinal cord.Brain research235(2), 378-386.

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