DL-AP5
Catalog Number : 7633136
description
DL-AP5 is the racemic version of AP5, a selective N-methyl-D-aspartate (NMDA) receptor antagonist that binds at glutamate site. DL-AP5 exhibits less potent NMDA receptor antagonist activity than the D-AP5 version and is used in the research of synaptic plasticity.
Additional Information
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Applications:
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FA
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Synonyms:
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APV acid, 2-Amino-5-phosphovaleric acid,
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Formulation:
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Crystalline solid
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Chemical Name:
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2-amino-5-phosphonopentanoic acid
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Molecular Formula:
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C5H12NO5P |
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Molecular Weight: |
197.1
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CAS Number
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76326-31-3
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Purity:
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≥95%
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Storage Conditions:
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Product should be kept at -20°C.
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References:
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Steele, R. J., & Morris, R. G. M. (1999). Delay‐dependent impairment of a matching‐to‐place task with chronic and intrahippocampal infusion of the NMDA‐antagonist D‐AP5. Hippocampus, 9(2), 118-136. Morris, R. G. (1989). Synaptic plasticity and learning: selective impairment of learning rats and blockade of long-term potentiation in vivo by the N-methyl-D-aspartate receptor antagonist AP5. The Journal of neuroscience,9(9), 3040-3057. Davies, J., & Watkins, J. C. (1982). Actions of D and L forms of 2-amino-5-phosphonovalerate and 2-amino-4-phosphonobutyrate in the cat spinal cord.Brain research, 235(2), 378-386. |