Dexamethasone

Grouped product items
Size Price Qty
500mg
$45.00
5g
$245.00
Catalog Number : 5000222

description

Dexamethasone is a synthetic anti-inflammatory and immunosuppressant steroid. It has a stronger affinity for the glucocorticoid receptor than the natural hydrocortisone ligand. Dexamethasone is reported to inhibit mature dendritic cell differentiation and to promote the differentiation of human mesenchymal cells.

Additional Information

Applications:
FA
Synonyms:
Decaject, Decameth, Decaspray, Dexasone, Hexadecadrol
Formulation:
Crystalline solid
Chemical Name:
(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
Molecular Formula:

C22H29FO5

Molecular Weight:
392.5
CAS Number
50-02-2
Purity:
≥98%
Storage Conditions:
Product should be kept at -20°C.
References:

Haynesworth, S. E., Baber, M. A., & Caplan, A. I. (1996). Cytokine expression by human marrow‐derived mesenchymal progenitor cells in vitro: Effects of dexamethasone and IL‐1α. Journal of cellular physiology166(3), 585-592.

Han, J., Thompson, P., & Beutler, B. (1990). Dexamethasone and pentoxifylline inhibit endotoxin-induced cachectin/tumor necrosis factor synthesis at separate points in the signaling pathway. The Journal of experimental medicine172(1), 391-394.

Larsson, E. L. (1980). Cyclosporin A and dexamethasone suppress T cell responses by selectively acting at distinct sites of the triggering process. The Journal of Immunology124(6), 2828-2833.

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