Purmorphamine

Grouped product items
SizePrice Qty
1mg
$25.00
10mg
$195.00
Catalog Number : 4831086

description

Purmorphamine is an activator of the Smoothened protein in the hedgehog signaling pathway. It is reported to induce osteogenesis and influence the differentiation and growth of neurons.
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Additional Information

Applications:
FA
Synonyms:
UNII-PB12M2F8KY, Shh Signaling Antagonist VI
Formulation:
Crystalline solid
Chemical Name:
9-cyclohexyl-N-(4-morpholin-4-ylphenyl)-2-naphthalen-1-yloxypurin-6-amine
Molecular Formula:

C31H32N6O2

Molecular Weight:
520.6
CAS Number
483367-10-8
Purity:
≥98%
Storage Conditions:
Product should be kept at -20°C.
References:

Wu, X., Walker, J., Zhang, J., Ding, S., & Schultz, P. G. (2004). Purmorphamine induces osteogenesis by activation of the hedgehog signaling pathway. Chemistry & biology11(9), 1229-1238.

Beloti, M. M., Bellesini, L. S., & Rosa, A. L. (2005). Purmorphamine enhances osteogenic activity of human osteoblasts derived from bone marrow mesenchymal cells. Cell biology international29(7), 537-541.

Oliveira, F. S., Bellesini, L. S., Defino, H. L. A., da Silva Herrero, C. F., Beloti, M. M., & Rosa, A. L. (2012). Hedgehog signaling and osteoblast gene expression are regulated by purmorphamine in human mesenchymal stem cells. Journal of cellular biochemistry113(1), 204-208.

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