Ponasterone A
Catalog Number : 1345658
description
Ponasterone A is an ecdysone analog, an insect steroid hormone that controls molting and metamorphosis. It can be utilized as an inducer of ecdysone-inducible mammalian expression systems.
Additional Information
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Applications:
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FA
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Synonyms:
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25-deoxyecdysterone, P1A
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Formulation:
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Crystalline solid
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Chemical Name:
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(2S,3R,5R,9R,10R,13R,14S,17S)-17-[(2R,3R)-2,3-dihydroxy-6-methylheptan-2-yl]-2,3,14-trihydroxy-10,13-dimethyl-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one
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Molecular Formula:
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C27H44O6 |
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Molecular Weight: |
464.6
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CAS Number
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13408-56-5
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Purity:
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≥95%
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Storage Conditions:
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Product should be kept at -20°C.
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References:
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Albanese, C., Reutens, A. T., Bouzahzah, B., Fu, M., D’AMICO, M. A. R. K., LINK, T., ... & Pestell, R. G. (2000). Sustained mammary gland-directed, ponasterone A-inducible expression in transgenic mice. The FASEB Journal, 14(7), 877-884. Nakanishi, K., Koreeda, M., Sasaki, S., Chang, M. L., & Hsu, H. Y. (1966). Insect hormones. The structure of ponasterone A, insect-moulting hormone from the leaves of Podocarpus nakaii Hay. Chemical Communications (London), (24), 915-917. Constantino, S., Santos, R., Gisselbrecht, S., & Gouilleux, F. (2001). The ecdysone inducible gene expression system: unexpected effects of muristerone A and ponasterone A on cytokine signaling in mammalian cells. European Cytokine Network, 12(2), 365-7. |