Ponasterone A
Catalog Number : 1345658
description
Ponasterone A is an ecdysone analog, an insect steroid hormone that controls molting and metamorphosis. It can be utilized as an inducer of ecdysone-inducible mammalian expression systems.
Additional Information
Applications: | FA |
Synonyms: | 25-deoxyecdysterone, P1A |
Formulation: | Crystalline solid |
Chemical Name: | (2S,3R,5R,9R,10R,13R,14S,17S)-17-[(2R,3R)-2,3-dihydroxy-6-methylheptan-2-yl]-2,3,14-trihydroxy-10,13-dimethyl-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one |
Molecular Formula: | C27H44O6 |
Molecular Weight: | 464.6 |
CAS Number | 13408-56-5 |
Purity: | ≥95% |
Storage Conditions: | Product should be kept at -20°C. |
References: | Albanese, C., Reutens, A. T., Bouzahzah, B., Fu, M., D’AMICO, M. A. R. K., LINK, T., ... & Pestell, R. G. (2000). Sustained mammary gland-directed, ponasterone A-inducible expression in transgenic mice. The FASEB Journal, 14(7), 877-884. Nakanishi, K., Koreeda, M., Sasaki, S., Chang, M. L., & Hsu, H. Y. (1966). Insect hormones. The structure of ponasterone A, insect-moulting hormone from the leaves of Podocarpus nakaii Hay. Chemical Communications (London), (24), 915-917. Constantino, S., Santos, R., Gisselbrecht, S., & Gouilleux, F. (2001). The ecdysone inducible gene expression system: unexpected effects of muristerone A and ponasterone A on cytokine signaling in mammalian cells. European Cytokine Network, 12(2), 365-7. |