OAC-2
Catalog Number : 6013929
description
OAC-2 is an Octamer-binding transcription factor 4 (OCT4) activator. It is reported to enhance the reprogramming efficiency of induced pluripotent stem cells (iPSCs) from fibroblasts and induces cardiomyocyte-like cells generation from fibroblasts when used in conjunction with other small molecules.
Additional Information
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Applications:
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FA
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Synonyms:
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OAC2, AK175881, N-1h-indol-5-yl-benzamide
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Formulation:
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Crystalline solid
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Chemical Name:
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N-(1H-indol-5-yl)benzamide
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Molecular Formula:
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C15H12N2O |
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Molecular Weight: |
236.3
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CAS Number
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6019-39-2
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Purity:
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≥98%
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Storage Conditions:
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Product should be kept at -20°C.
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References:
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Cao, N., Huang, Y., Zheng, J., Spencer, C. I., Zhang, Y., Fu, J. D., ... & Ma, T. (2016). Conversion of human fibroblasts into functional cardiomyocytes by small molecules. Science, 352(6290), 1216-1220. Li, W., Tian, E., Chen, Z. X., Sun, G., Ye, P., Yang, S., ... & Wang, C. (2012). Identification of Oct4-activating compounds that enhance reprogramming efficiency. Proceedings of the National Academy of Sciences, 109(51), 20853-20858. Takahashi, K., Tanabe, K., Ohnuki, M., Narita, M., Ichisaka, T., Tomoda, K., & Yamanaka, S. (2007). Induction of pluripotent stem cells from adult human fibroblasts by defined factors. cell, 131(5), 861-872. |