EC 23

Grouped product items
SizePrice Qty
5mg
$70.00
25mg
$245.00
Catalog Number : 1044131

description

EC 23 is a photostable synthetic analog of all-trans retinoic acid (ATRA). Retinoic Acid is vitamin A derivative that is an agonist for the retinoic acid receptors, which act as transcription factors that regulate the growth and differentiation of normal and malignant cells. It is reported to promote the differentiation of embryonic cells into motor neurons, pancreatic progenitors and cardiomyocytes.
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Additional Information

Applications:
FA
Synonyms:
AGN-190205, EC23
Formulation:
Crystalline solid
Chemical Name:
4-[2-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)ethynyl]benzoic acid
Molecular Formula:

C23H24O2

Molecular Weight:
332.4
CAS Number
104561-41-3
Purity:
≥98%
Storage Conditions:
Product should be kept at -20°C.
References:

Clemens, G., Flower, K. R., Henderson, A. P., Whiting, A., Przyborski, S. A., Jimenez-Hernandez, M., ... & Gardner, P. (2013). The action of all-trans-retinoic acid (ATRA) and synthetic retinoid analogues (EC19 and EC23) on human pluripotent stem cells differentiation investigated using single cell infrared microspectroscopy. Molecular BioSystems9(4), 677-692.

Maltman, D. J., Christie, V. B., Collings, J. C., Barnard, J. H., Fenyk, S., Marder, T. B., ... & Przyborski, S. A. (2009). Proteomic profiling of the stem cell response to retinoic acid and synthetic retinoid analogues: identification of major retinoid-inducible proteins. Molecular Biosystems5(5), 458-471.

Barnard, J. H., Collings, J. C., Whiting, A., Przyborski, S. A., & Marder, T. B. (2009). Synthetic retinoids: structure–activity relationships. Chemistry–A European Journal15(43), 11430-11442.

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