Rosiglitazone
description
Additional Information
Applications:
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FA
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Synonyms:
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Avandia, Rosiglizole, rosiglitazona, BRL49653, Gaudil
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Formulation:
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Crystalline solid
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Chemical Name:
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5-[[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
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Molecular Formula:
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C18H19N3O3S |
Molecular Weight: |
357.4
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CAS Number
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122320-73-4
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Purity:
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≥98%
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Storage Conditions:
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Product should be kept at -20°C.
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References:
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Fryer, L. G., Parbu-Patel, A., & Carling, D. (2002). The anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways. Journal of Biological Chemistry, 277(28), 25226-25232. DREAM (Diabetes REduction Assessment with ramipril and rosiglitazone Medication) Trial Investigators. (2006). Effect of rosiglitazone on the frequency of diabetes in patients with impaired glucose tolerance or impaired fasting glucose: a randomised controlled trial. The Lancet, 368(9541), 1096-1105. Wang, C. H., Ciliberti, N., Li, S. H., Szmitko, P. E., Weisel, R. D., Fedak, P. W., ... & Verma, S. (2004). Rosiglitazone facilitates angiogenic progenitor cell differentiation toward endothelial lineage a new paradigm in glitazone pleiotropy.Circulation, 109(11), 1392-1400. |