Ribavirin
Catalog Number : 3670451
description
Ribavirin is an antiviral guanosine ribonucleoside analog. It is a prodrug that metabolizes into a form resembling purine RNA nucleosides and interferes with RNA metabolism and induces mutations in RNA-dependent replication. It is currently being researched as a potential treatment for COVID-19.
Additional Information
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Applications:
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FA
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Synonyms:
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Rebetol, Tribavirin, Ribamidyl, Virazole, Copegus, Ribasphere
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Formulation:
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Crystalline solid
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Chemical Name:
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1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide
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Molecular Formula:
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C8H12N4O5 |
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Molecular Weight: |
244.2
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CAS Number
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36791-04-5
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Purity:
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95%
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Storage Conditions:
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Product should be kept at -20°C.
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References:
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Khalili, J. S., Zhu, H., Mak, A., Yan, Y., & Zhu, Y. (2020). Novel coronavirus treatment with ribavirin: Groundwork for evaluation concerning COVID‐19. Journal of medical virology. Glue, P. (1999). The clinical pharmacology of ribavirin. In Seminars in liver disease (Vol. 19, pp. 17-24). Crotty, S., Maag, D., Arnold, J. J., Zhong, W., Lau, J. Y., Hong, Z., ... & Cameron, C. E. (2000). The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen. Nature medicine, 6(12), 1375-1379. |