Ribavirin
Catalog Number : 3670451
description
Ribavirin is an antiviral guanosine ribonucleoside analog. It is a prodrug that metabolizes into a form resembling purine RNA nucleosides and interferes with RNA metabolism and induces mutations in RNA-dependent replication. It is currently being researched as a potential treatment for COVID-19.
Additional Information
Applications: | FA |
Synonyms: | Rebetol, Tribavirin, Ribamidyl, Virazole, Copegus, Ribasphere |
Formulation: | Crystalline solid |
Chemical Name: | 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide |
Molecular Formula: | C8H12N4O5 |
Molecular Weight: | 244.2 |
CAS Number | 36791-04-5 |
Purity: | 95% |
Storage Conditions: | Product should be kept at -20°C. |
References: | Khalili, J. S., Zhu, H., Mak, A., Yan, Y., & Zhu, Y. (2020). Novel coronavirus treatment with ribavirin: Groundwork for evaluation concerning COVID‐19. Journal of medical virology. Glue, P. (1999). The clinical pharmacology of ribavirin. In Seminars in liver disease (Vol. 19, pp. 17-24). Crotty, S., Maag, D., Arnold, J. J., Zhong, W., Lau, J. Y., Hong, Z., ... & Cameron, C. E. (2000). The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen. Nature medicine, 6(12), 1375-1379. |