Recombinant laminin-411 (BG iMatrix-411)
description
BG iMatrix 411 is a chemically defined, animal-free, and xeno-free laminin-411 E8 fragment. Laminin-411 exhitits high specificity and primarily binds to the cell surface transmembrane receptors integrin α6β1 and α71β. It can be used as a substrate for the proliferation and differentiation of bile duct endothelial cells and vascular endothelial cells. Switching from laminin-511 to laminin-411 during differentiation efficiently induces endothelial progenitor cells from iPS cells.
The 350ug size is supplied as 2x175ug vials. The 1050ug size is supplied as 6x175ug vials.
Additional Information
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Applications:
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Cell Culture
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| Research Interest: | Stem Cell Research |
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| Cell Type: | Stem Cells |
| Application: | Cell Culture |
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Application Notes:
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Formulation:
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0.5mg/mL in PBS(-).
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References:
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Takayama K. et al., Laminin 411 and 511 promote the cholangiocyte differentiation of human induced pluripotent stem cells. Biochemical and biophysical research communications, 474 (1), 91-96, 2016 Ohta R et al., Laminin-guided highly efficient endothelial commitment from human pluripotent stem cells. Scientific Reports, 6 (35680), 1-12, 2016 |