Recombinant laminin-411 (BG iMatrix-411)

Grouped product items
Size Price Qty
350 ug
1050 ug
Catalog Number : RL411


BG iMatrix 411 is a chemically defined, animal-free, and xeno-free laminin-411 E8 fragment. Laminin-411 exhitits high specificity and primarily binds to the cell surface transmembrane receptors integrin α6β1 and α71β. It can be used as a substrate for the proliferation and differentiation of bile duct endothelial cells and vascular endothelial cells. Switching from laminin-511 to laminin-411 during differentiation efficiently induces endothelial progenitor cells from iPS cells. 

The 350ug size is supplied as 2x175ug vials. The 1050ug size is supplied as 6x175ug vials. 

Additional Information

Cell Culture
Research Interest: Stem Cell Research
Cell Type: Stem Cells
Application: Cell Culture
Application Notes:
0.5mg/mL in PBS(-).

Takayama K. et al., Laminin 411 and 511 promote the cholangiocyte differentiation of human induced pluripotent stem cells. Biochemical and biophysical research communications, 474 (1), 91-96, 2016

Ohta R et al., Laminin-guided highly efficient endothelial commitment from human pluripotent stem cells. Scientific Reports, 6 (35680), 1-12, 2016

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