Recombinant laminin-221 (BG iMatrix-221)

Grouped product items
Size Price Qty
350 ug
1050 ug
Catalog Number : RL221


BG iMatrix 221 is a chemically defined, animal-free, and xeno-free laminin-221 E8 fragment. Laminin-332 primarily binds to the cell surface transmembrane receptors integrin α7X2β1. It can be used as a substrate for the proliferation and differentiation of cardiomyocytes and skeletal muscles.  

The 350ug size is supplied as 2x175ug vials. The 1050ug size is supplied as 6x175ug vials. 

Additional Information

Cell Culture
Research Interest: Stem Cell Research
Cell Type: Stem Cells
Application: Cell Culture
Application Notes:
0.5mg/mL in PBS(-).

1. Nishiuchi, R., Takagi, J., Hayashi, M., Ido, H., Yagi, Y., Sanzen N., Tsuji T., Yamada M., & Sekiguchi K. (2006). Ligand-binding specificities of laminin-binding integrins: A comprehensive survey of laminin–integrin interactions using recombinant α3β1, α6β1, α7β1 and α6β4 integrins. Matrix Biology, 25(3), 189-197.

2. Taniguchi, Y., Ido, H., Sanzen, N., Sato-Nishiuchi, R., Futaki, S., & Sekiguchi, K. (2009). The C-terminal Region of Laminin β Chains Modulates the Integrin Binding Affinities of Laminins. The Journal of Biological Chemistry, 284(12), 7820-31.

3. Israeli-Rosenberg, S., Manso, A. M., Okada, H., & Ross, R. (2014). Integrins and Integrin-Associated Proteins in the Cardiac Myocyte. Circular Research, 114(3), 572-586. 

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