AM 580
description
Additional Information
Applications:
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FA
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Synonyms:
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AM580; AM-580; AM 580; CD-336; CD336; NSC 608001
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Formulation:
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Crystalline solid
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Chemical Name:
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4-[(5,5,8,8-tetramethyl-6,7-dihydronaphthalene-2-carbonyl)amino]benzoic acid
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Molecular Formula:
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C22H25NO3 |
Molecular Weight: |
351.4
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CAS Number
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102121-60-8
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Purity:
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≥98%
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Storage Conditions:
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Product should be kept at -20°C.
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References:
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Gianni, M., Calzi, M. L., Terao, M., Guiso, G., Caccia, S., Barbui, T., ... & Garattini, E. (1996). AM580, a stable benzoic derivative of retinoic acid, has powerful and selective cyto-differentiating effects on acute promyelocytic leukemia cells. Blood, 87(4), 1520-1531. Wang, W., Yang, J., Liu, H., Lu, D., Chen, X., Zenonos, Z., ... & Bradley, A. (2011). Rapid and efficient reprogramming of somatic cells to induced pluripotent stem cells by retinoic acid receptor gamma and liver receptor homolog 1. Proceedings of the National Academy of Sciences, 108(45), 18283-18288. Tamura, K., Kagechika, H., Hashimoto, Y., Ohsugi, K., Shudo, K., & Ide, H. (1990). Synthetic retinoids, retinobenzoic acids, Am80, Am580 and Ch55 regulate morphogenesis in chick limb bud. Cell Differentiation and Development, 32(1), 17-26. |