Creating Value for Life Science Research!


Get a Free Sample of this product!
shopping cart image

Anti-Human CD4 APC



Catalog Number : 06111-80

Description

The OKT4 monoclonal antibody specifically binds to the CD4 receptor for the human immunodeficiency virus (HIV). CD4 is a 59 kDa single-chain transmembrane glycoprotein that expressed on the surface of most of the thymocytes, T-helper cells, and in low levels on monocytes and macrophages. CD4 is a co-receptor in the antigen-induced T cell activation (together with the MHC class II). The OKT4 and the RPA-T4 monoclonal antibodies recognize different epitopes of CD4 and they do not exhibit cross-block binding.

Additional Information

Clone
OKT4
Format:
APC
Applications
FC
Reactivity
Human
Isotype:
Mouse IgG2b, kappa
Research Interest: Adaptive Immunity
Cell Type: Monocytes and Macrophages, T Cells, Th17 cells, Treg cells
Protein Cross Reactivity: Chimpanzee, Cynomolgus, Rhesus
Preperation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Reinherz, E. L., Kung, P. C., Goldstein, G., & Schlossman, S. F. (1979). Separation of functional subsets of human T cells by a monoclonal antibody.Proceedings of the National Academy of Sciences76(8), 4061-4065.

 Knapp W (1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

Bour, S. T. E. P. H. A. N. E., Boulerice, F. R. A. N. C. O. I. S., & Wainberg, M. A. (1991). Inhibition of gp160 and CD4 maturation in U937 cells after both defective and productive infections by human immunodeficiency virus type 1.Journal of virology65(12), 6387-6396.


Availability: In stock

Size Price Qty
25 tests
$70.00
100 tests
$125.00
500 tests
$625.00
Additional OKT4 Formats
Cat.No. Format Starting From
06111-20Purified $ 65.00
06111-50FITC $ 40.00
06111-40BG Violet 450 $ 95.00
06111-80APC $ 70.00
06111-60PE $ 55.00
06111-70PerCP-Cyanine5.5 $ 80.00