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Anti-Human CD25 APC



Catalog Number : 07311-80

Description

The BC96 monoclonal antibody specifically reacts with the 55 kDa type I transmembrane glycoprotein known as the interleukin-2 receptor α (IL-2R α, also known as CD25). CD25 is expressed by the early progenitors of T and B lymphocytes lineage, and by activated mature T and B lymphocytes. CD25 is a low affinity interleukin-2 receptor, but its association with the IL-2 receptor β chain (CD122) and the common γ chain (CD 132) results in a high affinity IL-2R complex. CD25 plays an important role in B and T cell proliferation, differentiation, and activation.

Additional Information

Clone
BC96
Format:
APC
Applications
FC
Reactivity
Human
Isotype:
Mouse IgG1, kappa
Research Interest: Adaptive Immunity
Cell Type: B Cells, T Cells, Treg cells
Protein Cross Reactivity: Baboon, Chimpanzee, Cynomolgus, Rhesus
Preperation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Schlossman, S., L. Bloumsell, et al. eds (1995). Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York

Zhang, B., Zhang, X., Tang, F. L., Zhu, L. P., Liu, Y., & Lipsky, P. E. (2008). Clinical significance of increased CD4+ CD25− Foxp3+ T cells in patients with new-onset systemic lupus erythematosus. Annals of the rheumatic diseases,67(7), 1037-1040.

Chapel, A., Bensussan, A., Vilmer, E., & Dormont, D. (1992). Differential human immunodeficiency virus expression in CD4+ cloned lymphocytes: from viral latency to replication. Journal of virology66(6), 3966-3970.


Availability: In stock

Size Price Qty
25 tests
$90.00
100 tests
$180.00
Additional BC96 Formats
Cat.No. Format Starting From
07311-60PE $ 70.00
07311-77PE-Cyanine7 $ 115.00
07311-20Purified $ 75.00
07311-80APC $ 90.00
07311-70PerCP-Cyanine5.5 $ 200.00