Valproic acid sodium salt
description
Additional Information
Applications:
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FA
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Synonyms:
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2-Propylpentanoic Acid, Convulsofin, Depakene, Depakine, Divalproex, Ergenyl
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Formulation:
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Crystalline solid
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Chemical Name:
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sodium;2-propylpentanoate
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Molecular Formula:
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C8H15O2Na |
Molecular Weight: |
166.2
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CAS Number
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1069-66-5
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Purity:
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≥95%
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Storage Conditions:
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Product should be kept at -20°C.
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References:
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Phiel, C. J., Zhang, F., Huang, E. Y., Guenther, M. G., Lazar, M. A., & Klein, P. S. (2001). Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen. Journal of Biological Chemistry,276(39), 36734-36741. Göttlicher, M., Minucci, S., Zhu, P., Krämer, O. H., Schimpf, A., Giavara, S., ... & Heinzel, T. (2001). Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells. The EMBO journal, 20(24), 6969-6978. Bug, G., Gül, H., Schwarz, K., Pfeifer, H., Kampfmann, M., Zheng, X., ... & Ruthardt, M. (2005). Valproic acid stimulates proliferation and self-renewal of hematopoietic stem cells. Cancer Research, 65(7), 2537-2541. Huangfu, D., Maehr, R., Guo, W., Eijkelenboom, A., Snitow, M., Chen, A. E., & Melton, D. A. (2008). Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds. Nature biotechnology, 26(7), 795-797. |