IWP-3
description
Additional Information
Applications:
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FA
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Synonyms:
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Inhibitor of Wnt Production-3
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Formulation:
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Crystalline solid
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Chemical Name:
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2-[[3-(4-fluorophenyl)-3,4,6,7-tetrahydro-4-oxothieno[3,2-d]pyrimidin-2-yl]thio]-N-
(6-methyl-2-benzothiazolyl)-acetamide
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Molecular Formula:
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C22H17FN4O2S3 |
Molecular Weight: |
484.6
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CAS Number
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687561-60-0
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Purity:
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≥98%
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Storage Conditions:
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Product should be kept at -20°C.
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References:
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Chen, B., Dodge, M. E., Tang, W., Lu, J., Ma, Z., Fan, C. W., ... & Lum, L. (2009). Small molecule–mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer. Nature chemical biology, 5(2), 100-107. Willems, E., Spiering, S., Davidovics, H., Lanier, M., Xia, Z., Dawson, M., ... & Mercola, M. (2011). Small-molecule inhibitors of the Wnt pathway potently promote cardiomyocytes from human embryonic stem cell–derived mesoderm.Circulation research, 109(4), 360-364. Lanier, M., Schade, D., Willems, E., Tsuda, M., Spiering, S., Kalisiak, J., ... & Cashman, J. R. (2012). Wnt inhibition correlates with human embryonic stem cell cardiomyogenesis: a structure–activity relationship study based on inhibitors for the Wnt response. Journal of medicinal chemistry, 55(2), 697-708. |