TTNPB

Grouped product items
SizePrice Qty
1mg
$40.00
10mg
$155.00
Catalog Number : 7142861

description

TTNPB is a retinoic acid analog that selectively and potently activates the retinoic acid receptors. It is reported to increase the efficiency of induced pluripotent stem cell (iPSC) chemical reprogramming.
product image

Additional Information

Applications:
FA
Synonyms:
AGN-191183, Arotinoid acid, Arotinoic acid, Ro 13-7410
Formulation:
Crystalline solid
Chemical Name:
4-[(E)-2-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)prop-1-enyl]benzoic acid
Molecular Formula:

C24H28O2

Molecular Weight:
348.5
CAS Number
71441-28-6
Purity:
≥98%
Storage Conditions:
Product should be kept at -20°C.
References:

Pignatello, M. A., Kauffman, F. C., & Levin, A. A. (1997). Multiple factors contribute to the toxicity of the aromatic retinoid, TTNPB (Ro 13-7410): binding affinities and disposition. Toxicology and applied pharmacology142(2), 319-327.

Åström, A., Pettersson, U., Krust, A., Chambon, P., & Voorhees, J. J. (1990). Retinoic acid and synthetic analogs differentially activate retinoic acid receptor dependent transcription. Biochemical and biophysical research communications173(1), 339-345.

Hossain, M. Z., & Bertram, J. S. (1994). Retinoids suppress proliferation, induce cell spreading, and up-regulate connexin43 expression only in postconfluent 10T1/2 cells: implications for the role of gap junctional communication. Cell growth & differentiation: the molecular biology journal of the American Association for Cancer Research5(11), 1253-1261.

© BioGems International, Inc. All rights reserved.