All-Trans Retinoic Acid

Grouped product items
SizePrice Qty
50mg
$35.00
1g
$95.00
Catalog Number : 3027949

description

Retinoic Acid is vitamin A derivative that is an agonist for the retinoic acid receptors, which act as transcription factors that regulate the growth and differentiation of normal and malignant cells. It is reported to promote the differentiation of embryonic cells into motor neurons, pancreatic progenitors and cardiomyocytes.
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Additional Information

Applications:
FA
Synonyms:
NSC 122578, Vitamin A Acid, Tretinoin, ATRA
Formulation:
Crystalline solid
Chemical Name:
(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid
Molecular Formula:

C20H28O2

Molecular Weight:
300.4
CAS Number
302-79-4
Purity:
≥98%
Storage Conditions:
Product should be kept at -20°C.
References:

Dani, C., Smith, A. G., Dessolin, S., Leroy, P., Staccini, L., Villageois, P., ... & Ailhaud, G. (1997). Differentiation of embryonic stem cells into adipocytes in vitro. Journal of cell science110(11), 1279-1285.

Wobus, A. M., Kaomei, G., Shan, J., Wellner, M. C., Rohwedel, J., Guanju, J., ... & Franz, W. M. (1997). Retinoic acid accelerates embryonic stem cell-derived cardiac differentiation and enhances development of ventricular cardiomyocytes. Journal of molecular and cellular cardiology29(6), 1525-1539.

Takahashi, J., Palmer, T. D., & Gage, F. H. (1999). Retinoic acid and neurotrophins collaborate to regulate neurogenesis in adult‐derived neural stem cell cultures. Journal of neurobiology38(1), 65-81.

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