OAC-1

Grouped product items
SizePrice Qty
10mg
$145.00
25mg
$325.00
Catalog Number : 3009078

description

OAC-1 activates OCT-4, a transcription factor involved in the self-renewal of undifferentiated stem cells. It is commonly used to enhance the efficiency of reprogramming embryonic fibroblasts. OAC-1 does not seem to effect Wnt-Beta-catenin signaling or the pt3-p21 pathway.
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Additional Information

Applications:
FA
Synonyms:
BAS 00287861, OAC1, AC1LG6VC
Formulation:
Crystalline solid
Chemical Name:
N-(1H-pyrrolo[2,3-c]pyridin-5-yl)benzamide
Molecular Formula:

C14H11N3O

Molecular Weight:
237.3
CAS Number
300586-90-7
Purity:
≥98%
Storage Conditions:
Product should be kept at -20°C.
References:

Li, W., Tian, E., Chen, Z. X., Sun, G., Ye, P., Yang, S., ... & Shi, Y. (2012). Identification of Oct4-activating compounds that enhance reprogramming efficiency. Proceedings of the National Academy of Sciences109(51), 20853-20858.

Huang, X., Cooper, S., & Broxmeyer, H. E. (2014). Activation of OCT4 Enhances Ex Vivo Expansion of Phenotypically Defined and Functionally Engraftable Human Cord Blood Hematopoietic Stem and Progenitor Cells By Regulating HOXB4 Expression. Blood124(21), 4332-4332.

Takahashi, K., Tanabe, K., Ohnuki, M., Narita, M., Ichisaka, T., Tomoda, K., & Yamanaka, S. (2007). Induction of pluripotent stem cells from adult human fibroblasts by defined factors. cell131(5), 861-872.

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