Tranylcypromine hydrochloride

Grouped product items
Size Price Qty
100mg
$30.00
250mg
$70.00
Catalog Number : 1984764

description

Tranylcypromine hydrochloride is a cell-permeable inhibitor of histone demethylzation. It is reported to be an irreversible inhibitor of monoamine oxidase (MAO) and lysine-specific demethylase 1. It is also useful in chemically reprogramming murine fibroblasts to induced pluripotent stem cells.

Additional Information

Applications:
FA
Synonyms:
Parnate, (1R,2S)-rel-2-phenylcyclopropanamine monohydrochloride, Tranylcypromine hydrochloride, 2-PCPA
Formulation:
Crystalline solid
Chemical Name:
trans-2-Phenylcyclopropylamine hydrochloride
Molecular Formula:

C9H11N HCl

Molecular Weight:
169.7
CAS Number
1986-47-6
Purity:
≥98%
Storage Conditions:
Product should be kept at -20°C.
References:

Hou, P., Li, Y., Zhang, X., Liu, C., Guan, J., Li, H., ... & Deng, H. (2013). Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds. Science341(6146), 651-654.

Zhou, H., Li, W., Zhu, S., Joo, J. Y., Do, J. T., Xiong, W., ... & Ding, S. (2010). Conversion of mouse epiblast stem cells to an earlier pluripotency state by small molecules. Journal of Biological Chemistry285(39), 29676-29680.

Schmidt, D. M., & McCafferty, D. G. (2007). trans-2-Phenylcyclopropylamine is a mechanism-based inactivator of the histone demethylase LSD1.Biochemistry46(14), 4408-4416.

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