SR 95531 Hydrobromide

Grouped product items
SizePrice Qty
10mg
$105.00
50mg
$390.00
Catalog Number : 1045090

description

SR 95531 is a selective GABAA receptor antagonist, inhibiting chloride flux across the cell membrane and neuronal hyperpolarization. It is reported to elicit convulsions in mice and rats.
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Additional Information

Applications:
FA
Synonyms:
SR-95531, Gabazine bromide
Formulation:
Crystalline solid
Chemical Name:
4-[6-amino-3-(4-methoxyphenyl)pyridazin-1-ium-1-yl]butanoic acid;bromide
Molecular Formula:

C15H17N3O3 HBr

Molecular Weight:
368.2
CAS Number
104104-50-9
Purity:
≥98%
Storage Conditions:
Product should be kept at -20°C.
References:

Heaulme, M., Chambon, J. P., Leyris, R., Wermuth, C. G., & Biziere, K. (1987). Characterization of the binding of [3H] SR 95531, a GABAA antagonist, to rat brain membranes. Journal of neurochemistry48(6), 1677-1686.

Hamann, M., Desarmenien, M., Desaulles, E., Bader, M. F., & Feltz, P. (1988). Quantitative evaluation of the properties of a pyridazinyl GABA derivative (SR 95531) as a GABAA competitive antaginist. An electrophysiological approach. Brain research442(2), 287-296.

Mienville, J. M., & Vicini, S. (1987). A pyridazinyl derivative of gamma-aminobutyric acid (GABA), SR 95531, is a potent antagonist of Cl− channel opening regulated by GABAA receptors. Neuropharmacology26(7), 779-783.

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