Sodium Butyrate

Grouped product items
SizePrice Qty
50g
$25.00
250g
$95.00
Catalog Number : 1565474

description

Sodium Butyrate is the sodium salt of butyric acid that has the biological effect of inducing histone hyperacetylation and the inhibition of histone deacetylase (HDAC) activity. It is reported to induce apoptosis in a variety of cell lines and induce pancreatic progenitor formation. In combination with Activin A, sodium butyrate promotes the differentiation of hepatocytes from embryonic stem cells.
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Additional Information

Applications:
FA
Synonyms:
Butyric Acid, Sodium butanoate
Formulation:
Crystalline solid
Chemical Name:
Butanoic acid
Molecular Formula:

C4H7O2 Na

Molecular Weight:
110.1
CAS Number
156-54-7
Purity:
≥95%
Storage Conditions:
Product should be kept at room temperature.
References:

Candido, E. P. M., Reeves, R., & Davie, J. R. (1978). Sodium butyrate inhibits histone deacetylation in cultured cells. Cell14(1), 105-113.

Hague, A., Manning, A. M., Hanlon, K. A., Hart, D., Paraskeva, C., & Huschtscha, L. I. (1993). Sodium butyrate induces apoptosis in human colonic tumour cell lines in a p53‐independent pathway: implications for the possible role of dietary fibre in the prevention of large‐bowel cancer. International Journal of Cancer55(3), 498-505.

Rambhatla, L., Chiu, C. P., Kundu, P., Peng, Y., & Carpenter, M. K. (2003). Generation of hepatocyte-like cells from human embryonic stem cells. Cell transplantation12(1), 1-11.

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