Sinomenine hydrochloride

Grouped product items
Size Price Qty
50mg
$30.00
500mg
$180.00
Catalog Number : 6083373

description

Sinomenine is an anti-inflammatory plant alkaloid that suppresses the production of proinflammatory cytokines and ease arthritis inflammation. It is reported to also be used to promote the self-renewal of embryonic stem cells

Additional Information

Applications:
FA
Synonyms:
cocculine hydrochloride, NSC 76021, NSC76021
Formulation:
Crystalline solid
Chemical Name:
9-alpha,13-alpha,14-alpha-Morphinan-6-one,7,8-didehydro-3,7-dimethoxy-4-hydroxy-17-methyl-,hydrochloride
Molecular Formula:

C19H23NO4HCl

Molecular Weight:
365.9
CAS Number
6080-33-7
Purity:
≥98%
Storage Conditions:
Product should be kept at -20°C.
References:

Liu, L., Resch, K., & Kaever, V. (1994). Inhibition of lymphocyte proliferation by the anti-arthritic drug sinomenine. International journal of immunopharmacology,16(8), 685-691.

Vieregge, B., Resch, K., & Kaever, V. (1999). Synergistic effects of the alkaloid sinomenine in combination with the immunosuppressive drugs tacrolimus and mycophenolic acid. Planta medica65(1), 80-82.

Wang, Y., Fang, Y., Huang, W., Zhou, X., Wang, M., Zhong, B., & Peng, D. (2005). Effect of sinomenine on cytokine expression of macrophages and synoviocytes in adjuvant arthritis rats. Journal of ethnopharmacology98(1), 37-43.

Desbordes, S. C., Placantonakis, D. G., Ciro, A., Socci, N. D., Lee, G., Djaballah, H., & Studer, L. (2008). High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells. Cell stem cell2(6), 602-612.

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