Rolipram

Grouped product items
SizePrice Qty
10mg
$50.00
25mg
$110.00
Catalog Number : 6145453

description

Rolipram is a selective Type 4 cyclic nucleotide phosphodiesterases (PDE4) inhibitor, affective isoform A over other isoforms. It is reported to inhibit inflammation and induces neural differentiation of bone marrow-derived mesenchymal stem cells.
product image

Additional Information

Applications:
FA
Synonyms:
ZK 62711, Rolipramum,
Formulation:
Crystalline solid
Chemical Name:
4-(3-cyclopentyloxy-4-methoxyphenyl)pyrrolidin-2-one
Molecular Formula:

C16H21NO3

Molecular Weight:
275.3
CAS Number
61413-54-5
Purity:
≥98%
Storage Conditions:
Product should be kept at -20°C.
References:

Hou, P., Li, Y., Zhang, X., Liu, C., Guan, J., Li, H., ... & Ge, J. (2013). Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds. Science341(6146), 651-654.

Sommer, N., Löschmann, P. A., Northoff, G. H., Weller, M., Steinbrecher, A., Steinbach, J. P., ... & Dichgans, J. (1995). The antidepressant rolipram suppresses cytokine production and prevents autoimmune encephalomyelitis. Nature medicine1(3), 244.

Semmler, J., Wachtell, H., & Endres, S. (1993). The specific type IV phosphodiesterase inhibitor rolipram suppresses tumor necrosis factor-α production by human mononuclear cells. International journal of immunopharmacology15(3), 409-413.

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