RG108
description
Additional Information
Applications:
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FA
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Synonyms:
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RG-108, RG 108, CHEMBL1564869, NCI401077
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Formulation:
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Crystalline solid
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Chemical Name:
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(2S)-2-(1,3-dioxoisoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid
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Molecular Formula:
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C19H14N2O4 |
Molecular Weight: |
334.3
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CAS Number
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48208-26-0
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Purity:
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≥98%
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Storage Conditions:
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Product should be kept at -20°C.
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References:
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Schirrmacher, E., Beck, C., Brueckner, B., Schmitges, F., Siedlecki, P., Bartenstein, P., ... & Schirrmacher, R. (2006). Synthesis and in vitro evaluation of biotinylated RG108: a high affinity compound for studying binding interactions with human DNA methyltransferases. Bioconjugate chemistry,17(2), 261-266. Asgatay, S., Champion, C., Marloie, G., Drujon, T., Senamaud-Beaufort, C., Ceccaldi, A., ... & Guianvarc’h, D. (2014). Synthesis and evaluation of analogues of N-phthaloyl-l-tryptophan (RG108) as inhibitors of DNA methyltransferase 1. Journal of medicinal chemistry, 57(2), 421-434. Shi, Y., Desponts, C., Do, J. T., Hahm, H. S., Schöler, H. R., & Ding, S. (2008). Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds. Cell stem cell, 3(5), 568-574. |