PluriSln 1

Grouped product items
SizePrice Qty
10mg
$100.00
50mg
$270.00
Catalog Number : 9138826

description

PluriSln 1 a stearoyl-CoA desaturase 1 (SCD1) inhibitor used to selectively eliminate undifferentiated human pluripotent stem cells. It induces apoptosis in hPSCs to the exclusion of differentiated or progenitor cells. It is reported to prevent teratoma formation in immunocompromised mice.
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Additional Information

Applications:
FA
Synonyms:
NSC 14613, 4-Pyridinecarboxylicacid, 2-phenylhydrazide
Formulation:
Crystalline solid
Chemical Name:
N'-phenylpyridine-4-carbohydrazide
Molecular Formula:

C12H11N3O

Molecular Weight:
213.2
CAS Number
91396-88-2
Purity:
≥95%
Storage Conditions:
Product should be kept at -20°C.
References:

Ben-David, U., Gan, Q. F., Golan-Lev, T., Arora, P., Yanuka, O., Oren, Y. S., ... & Benvenisty, N. (2013). Selective elimination of human pluripotent stem cells by an oleate synthesis inhibitor discovered in a high-throughput screen.Cell Stem Cell12(2), 167-179.

Phillips, M. I. (2014). Tumor-free iPS stem cells for heart cells. Cell Cycle,13(10), 1519-1519.

Lou, K. J. (2013). Small molecules vs. teratomas. SciBX: Science-Business eXchange6(7).

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