Pifithrin-mu
description
Additional Information
Applications:
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FA
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Synonyms:
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pifithrin-mu, 2-phenylacetylenesulfonamide, NSC 303580
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Formulation:
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Crystalline solid
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Chemical Name:
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2-phenylethynesulfonamide
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Molecular Formula:
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C8H7NO2S |
Molecular Weight: |
181.2
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CAS Number
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64984-31-2
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Purity:
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≥98%
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Storage Conditions:
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Product should be kept at -20°C.
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References:
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Strom, E., Sathe, S., Komarov, P. G., Chernova, O. B., Pavlovska, I., Shyshynova, I., ... & Gudkov, A. V. (2006). Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation. Nature chemical biology, 2(9), 474-479. Leu, J. J., Pimkina, J., Pandey, P., Murphy, M. E., & George, D. L. (2011). HSP70 inhibition by the small-molecule 2-phenylethynesulfonamide impairs protein clearance pathways in tumor cells. Molecular Cancer Research, 9(7), 936-947. Sekihara, K., Harashima, N., Tamaki, Y., Hieda, Y., Uchida, N., Inomata, T., & Harada, M. (2013, September). Antitumor effect induced by combination of radiation with a novel HSP70 inhibitor pifithrin-mu on human prostate cancer. InEUROPEAN JOURNAL OF CANCER (Vol. 49, pp. S232-S233). THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND: ELSEVIER SCI LTD. |